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Home All anti-UNC13D antibodies

Anti-UNC13D Antibody EPR4915

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SKU Description Amount Price Availability*  
TA307785
  • Rabbit monoclonal antibody against Munc 13-4(clone EPR4915)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403710) , 20ug
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)
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Also for UNC13D (NM_199242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human Munc 13-4 was used as an immunogen.
Clone NameEPR4915 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:50 - 100, IHC: 1:50 - 100, IP: 1:10 - 100, WB: 1:1,000 - 10,000,
BufferStore at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens unc-13 homolog D (C. elegans) (UNC13D)
Alternative NameFHL3; HLH3; HPLH3; Munc13-4
Database LinkNP_954712
FunctionMunc 13-4, also known as protein unc-13 homolog D, is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis, and it is involved in the regulation of cytolytic granules secretion. Mutations in Munc 13-4 are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Related Pathway

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WB Image
Western blot analysis on (A) Jurkat, (B) HuT-78, (C) JAR, (D) human placenta, and (E) human tonsil lysates using anti-Munc 13-4 RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Munc 13-4 RabMAb .

 

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