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AMACR UltraMAB Antibody, Clone UMAB68
UltraMAB Antibodies - Validated with 10K Protein Chip
Also for AMACR (NM_014324)
|Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.|
||0.5~1.0 mg/ml (Lot Dependent)
|| IHC 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1|
|AMACRD; CBAS4; RACE; RM|
|This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]. |
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-AMACR mouse monoclonal antibody. (UM800012; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded of human kidney using anti-AMACR clone UMAB68 mouse monoclonal antibody at 1:200 dilution of 1.0mg/mL using Polink2 Broad HRP DAB detection kit. UM800012 requires heat-induced epitope retrieval with Citrate pH6.0 in a pressure chamber/cooker high 3min. The image shows strong cytoplsamic staining in the kidney tubual cells.
Immunofluorescent staining of HeLa cells using anti-AMACR mouse monoclonal antibody (UM800012, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue).