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UltraMAB

ERG UltraMAB Antibody, Clone UMAB76

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500064
  • ERG mouse monoclonal antibody,clone UMAB76, 100 ul
468 In Stock Add to Shopping Cart
UM570064
  • ERG mouse monoclonal antibody,clone UMAB76, 30 ul
$120 In Stock Add to Shopping Cart
IHC(2)
10K-CHIP(1)
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Also for ERG (NM_182918)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog (ERG), transcript variant 1
Synonymserg-3; p55
ImmunogenFull length human recombinant protein of human ERG(NP_891548) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone UMAB76 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *IHC, 10K-CHIP Suggested Dilutions IHC 1:100,
BackgroundThis gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan

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IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ERG mouse monoclonal antibody. (UM500064)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-ERG mouse monoclonal antibody. (UM500064)
10K-CHIP Image
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-ERG mouse monoclonal antibody (UM500064). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

 

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