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UltraMAB

ALDH1L1 UltraMAB Antibody, Clone UMAB43

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500039
  • ALDH1L1 mouse monoclonal antibody, clone UMAB43, 100 ul
$468 In Stock Add to Shopping Cart
UM570039
  • ALDH1L1 mouse monoclonal antibody, clone UMAB43, 30 ul
$120 In Stock Add to Shopping Cart
WB(2)
Data Img
IHC(4)
Data Img
IF(1)
Data Img
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Also for ALDH1L1 (NM_012190)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell.
Clone NameClone UMAB43 IsotypeIgG2b
Species ReactivityHuman, Mouse, Rat, Monkey, Dog Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500, IHC 1:400, IF 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 1 family, member L1 (ALDH1L1), transcript variant 2
Alternative Name10-fTHF; 10-FTHFDH; FDH; FTHFD
Database LinkNP_036322
FunctionThe protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
Related Pathway

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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ALDH1L1 monoclonal antibody (Clone UMAB43).
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Western Blot analysis of 10 different human tissue lysates (10ug) by using anti-ALDH1L1 monoclonal antibody (clone UMAB43, 1:500)
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Immunohistochemical staining of paraffin-embedded Human adult brain tissue using anti-ALDH1L1 mouse monoclonal antibody. (UM500039; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded human embryonic liver tissue using ALDH1L1 clone UMAB43 mouse monoclonal antibody. Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min in pressure chamber/cooker. UM500039 was diluted 1:400 and detection shown with HRP enzyme and DAB chromogen. Strong cytoplasmic and membranous staining is seen in the hepatocyte.
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Immunohistochemical staining of paraffin-embedded human embryonic brain cortex tissue using ALDH1L1 clone UMAB43 mouse monoclonal antibody. Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min in pressure chamber/cooker. UM500039 was diluted 1:400 and detection shown with HRP enzyme and DAB chromogen. Strong cytoplasmic and membranous staining is seen in the in the glia, nueronal, and endothelial cells.
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Immunohistochemical staining of paraffin-embedded Human embryonic cerebellum using anti-ALDH1L1 mouse monoclonal antibody. (UM500039; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunofluorescent staining of A549 cells using ALDH1L1 mouse monoclonal antibody (UM500039, green). Actin filaments were labeled with TRITC-phalloidin (red), and nuclear with DAPI (blue). The three-color overlay image is located at the bottom-right corner.
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