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UltraMAB

ERCC1 UltraMAB Antibody, Clone 4F9

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (2) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500008
  • anti-ERCC1 mouse monoclonal antibody, clone 4F9, 100 ul
$468 In Stock Add to Shopping Cart
UM570008
  • anti-ERCC1 mouse monoclonal antibody, clone 4F9, 30 ul
$120 In Stock Add to Shopping Cart
WB(1)
IHC(12)
IF(1)
10K-CHIP(1)
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Also for ERCC1 (NM_001983)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens excision repair cross-complementation group 1 (ERCC1), transcript variant 2
SynonymsCOFS4; RAD10; UV20
ImmunogenProtein expressed in 293T cell transfected with human ERCC1 expression vector
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 4F9 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, 10K-CHIP Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100,
BackgroundThe product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ERCC1 monoclonal antibody (Clone 4F9).
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IF Image
Immunofluorescent staining of HeLa cells using anti-ERCC1 mouse monoclonal antibody (UM500008, Clone 4F9).
10K-CHIP Image
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-ERCC1 mouse monoclonal antibody (Clone 4F9). The positive reactive proteins are highlighted with red arrows in the enlarged subarray. Other positive controls spotted in this subarray are serial dilutions of mouse IgG as controls.

 

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