OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody UltraMAB

UltraMAB

TP63 UltraMAB Antibody, Clone UMAB4

UltraMAB™ Antibodies - Validated with 10K Protein Chip

div

 
Specifications Citations Customer Reviews Product Documents
SKU Description Datasheet Price Availability*  
UM500004
  • TP63 mouse monoclonal antibody, clone UMAB4, 100 ul
$468 2 Weeks Add to Shopping Cart
UM570004
  • TP63 mouse monoclonal antibody, clone UMAB4, 30 ul
$120 2 Weeks Add to Shopping Cart
WB(1)
Data Img
IHC(2)
Data Img
Write Review & Get Rewarded
X

Write a review and get rewarded!

Review this antibody and earn an OriGene coupon or Amazon giftcard

Follow these easy steps to reward yourself:

  1. Sign in to your account, or register for a new account;
  2. Write a review;
  3. Receive a coupon or giftcard once your review is accepted.

Click the button to start writing a review


OriGene Data

ImmunogenFull length human recombinant protein of human TP63 (NP_003713) produced in HEK293T cell.
Clone NameClone UMAB4 IsotypeIgG2a
Species ReactivityHuman , Dog , Monkey Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:1000~2000; IHC 1:150
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor protein p63 (TP63), transcript variant 1
Alternative NameAIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4
Database LinkNP_003713
FunctionThis gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TP63 monoclonal antibody (Clone UMAB4).
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-TP63 mouse monoclonal antibody (Clone UMAB4; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min).
spacer
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-TP63 mouse monoclonal antibody (Clone UMAB4; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min).
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title