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Home Antibody UltraMAB

UltraMAB

CA12 UltraMAB Antibody, Clone UMAB121

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500086
  • CA12 mouse monoclonal antibody,clone UMAB121, 100 ul
$468 In Stock Add to Shopping Cart
UM570086
  • CA12 mouse monoclonal antibody,clone UMAB121, 30 ul
$120 In Stock Add to Shopping Cart
WB(1)
Data Img
IHC(4)
Data Img
IF(1)
Data Img

OriGene Data

ImmunogenFull length human recombinant protein of human CA12(NP_001209) produced in HEK293T cell.
Clone NameClone UMAB121 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested Dilutions IHC 1:100~200,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens carbonic anhydrase XII (CA12), transcript variant 1
Alternative NameCAXII; HsT18816
Database LinkNP_001209
FunctionCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot of cell lysates (35ug) from A549. Diluation: 1:500
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CA12 mouse monoclonal antibody. (UM500086; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CA12 mouse monoclonal antibody. (UM500086; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CA12 mouse monoclonal antibody. (UM500086; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-CA12 mouse monoclonal antibody. (UM500086; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunofluorescent staining of HeLa cells using anti-CA12 mouse monoclonal antibody (UM500086, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue). Scale bar, 20µm.
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