A PKG inhibitor increases Ca2+-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition Am J Physiol Gastrointest Liver Physiol, May 2013; 304: G773 - G780.
[PDE2A]
Lck tyrosine kinase mediates ß1-integrin signalling to regulate Schwann cell migration and myelination Nature Communications 4, 1912 doi:10.1038/ncomms2928
[OCT6]
Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours J. Clin. Pathol., May 2013; 66: 386 - 391.
[Notch 1]
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis J. Leukoc. Biol., May 2013; 93: 771 - 780.
[anti-DDK]
UltraMAB™ Antibodies - Validated with 10K Protein Chip
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB26, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB26, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB26, Dilution 1:100)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-FOLH1 mouse monoclonal antibody (Clone UMAB26). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-FOLH1 (Clone UMAB26) very specifically recognizes FOLH1 antigen on OriGene protein microarray chip.
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq].
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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-FOLH1 mouse monoclonal antibody (Clone UMAB26). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-FOLH1 (Clone UMAB26) very specifically recognizes FOLH1 antigen on OriGene protein microarray chip.
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