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Anti-UBR5 Antibody EPR4841
Also for UBR5 (NM_015902)
|A synthetic peptide corresponding to residues in human URB5 was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens ubiquitin protein ligase E3 component n-recognin 5 (UBR5), transcript variant 1|
|DD5; EDD; EDD1; HYD|
Entrez Gene 51366 Human
Entrez Gene 70790 Mouse
|URB5 is a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. URB5 is localized and is disrupted in a variety of cancers. It potentially has a role in regulation of cell proliferation or differentiation (1).|
|Druggable Genome Ubiquitin mediated proteolysis|
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Western blot - Anti-EDD antibody [EPR4841]; All lanes : Anti-EDD antibody [EPR4841] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-rabbit at 1/2000 dilution.Predicted band size : 309 kDa.