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Home Antibody All anti-Tlr7 antibodies

Anti-Tlr7 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306156 Rabbit Polyclonal TLR7 Antibody 100ug $325 3-7 Days
LC413888 TLR7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenTLR7 antibody was raised against a peptide corresponding to 14 amino acids near the middle of mouse TLR7.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 2 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor 7 (TLR7)
Alternative NameTLR7-like
Database LinkNP_057646
Entrez Gene 51284 Human
Entrez Gene 170743 Mouse
FunctionToll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome (6) and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus (7). Activation of TLR7 by VSV results in stimulation of the immune response including IFNΑ secretion, suggesting the importance of TLR7 in virus recognition.
Related PathwayTransmembraneDruggable Genome Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TLR7 in Daudi cell lysates with TLR7 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
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Immunocytochemistry staining of Daudi cells using TLR7 antibody at 2 ug/mL.
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