OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-Tlr4 antibodies

Anti-Tlr4 Antibody

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA318891
  • Rabbit polyclonal anti-TLR4 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC408575) , 20ug Explanation
100ug $325 3-7 Days
Add to Shopping Cart
spacer
WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to residues surrounding amino acids 819 of rat TLR4
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-TLR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens toll-like receptor 4 (TLR4), transcript variant 3
Alternative NameARMD10; CD284; TLR-4; TOLL
Database LinkNP_003257
Entrez Gene 7099 Human
Entrez Gene 21898 Mouse
Entrez Gene 29260 Rat
FunctionTLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
Related PathwayTransmembraneDruggable Genome Toll-like receptor signaling pathwayPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TLR4 in rat kidney tissue lysate.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title