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Home Antibody All anti-Tlr3 antibodies

Anti-Tlr3 Antibody

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SKU Description Amount Price Availability*  
TA318910
  • Rabbit polyclonal anti-TLR3 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418801) , 20ug Explanation
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 805 of mouse TLR3
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB
BufferPBS, pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal
Purification Affinity purified

Reference Data

Target NameHomo sapiens toll-like receptor 3 (TLR3)
Alternative NameCD283; IIAE2
Database LinkNP_003256
Entrez Gene 7098 Human
Entrez Gene 142980 Mouse
Entrez Gene 364594 Rat
FunctionTo date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.
Related PathwayTransmembraneDruggable Genome Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TLR3 expression in lysate from Jurkat cells (Lane 1 & 2) and 3T3 cells (Lane 3).
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