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Home Antibody All anti-TTR antibodies

Anti-TTR Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306775 Chicken Polyclonal Transthyretin Antibody 100ug $325 3-7 Days
LC400134 TTR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenTransthyretin antibody was raised against a 17 amino acid peptide near the center of human Transthyretin .
Clone Name IsotypeIgY
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens transthyretin (TTR)
Alternative NameCTS; CTS1; HEL111; HsT2651; PALB; TBPA
Database LinkNP_000362
Entrez Gene 7276 Human
Entrez Gene 22139 Mouse
Entrez Gene 24856 Rat
FunctionTransthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson’s disease, schizophrenia, and depression.
Related PathwaySecreted ProteinES Cell Differentiation/IPS

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Transthyretin in human lung tissue lysate with Transthyretin antibody at (A) 1 and (B) 2 ug/ml.
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Immunohistochemistry of Transthyretin in human lung tissue with Transthyretin antibody at 2.5 ug/ml.
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