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Anti-TSN Antibody Polyclonal
|Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 0.5 - 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|Translin Antibody is supplied in PBS containing 0.02% sodium azide.|
|Translin Antibody is affinity chromatography purified via peptide column.
|Homo sapiens translin (TSN), transcript variant 1|
|BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN|
|Translin Antibody: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.|
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Western blot analysis of Translin in rat lung tissue lysate with Translin antibody at (A) 0.5 and (B) 1 ug/mL
Immunohistochemistry of Translin in human lung tissue with Translin antibody at 5 ug/mL.
Immunofluorescence of Translin in human lung tissue with Translin antibody at 20 ug/mL.