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Anti-TSG101 Antibody EPR7130(B)
Also for TSG101 (NM_006292)
|A synthetic peptide corresponding to residues in human TSG101 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens tumor susceptibility 101 (TSG101)|
|TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. It contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility protein appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression (1).|
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Western blot - Anti-TSG101 antibody [EPR7130(B)]; All lanes : Anti-TSG101 antibody [EPR7130(B)] at 1/1000 dilution.Lane 1 : Human Brain lysate.Lane 2 : K562 lysate.Lane 3 : Jurkat lysate.Lane 4 : SH-SY5Y lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 44 kDa.Observed band size : 45 kDa .
Other-Anti-TSG101 antibody [EPR7130(B)](ab125011); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-TSG101 antibody [EPR7130(B)]; Flow cytometric analysis of permeabilized K562 cells using ab125011 at 1/10 shown in red or a rabbit IgG negative shown in green.