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Home Antibody All anti-TRPM8 antibodies

Anti-TRPM8 Antibody

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302225
  • Rabbit Polyclonal Antibody against TRPM8 (Center R536)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402977) , 20ug Explanation
100ug 325 In Stock
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WB(2)
IHC(1)

OriGene Data

ImmunogenThis TRPM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-552 amino acids from the Central region of human TRPM8.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 127685 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens transient receptor potential cation channel, subfamily M, member 8 (TRPM8)
Alternative NameLTRPC6; TRPP8
Database LinkNP_076985
Entrez Gene 79054 Human
FunctionTRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Related PathwayIon Channels: Transient receptor potentialTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (Center R536)(Cat.#TA302225).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies).
WB Image
Western blot analysis of lysate from human brain tissue lysate, using TRPM8 Antibody (Center R536)(Cat. #TA302225). TA302225 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
IHC Image
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (Center R536) (Cat.#TA302225), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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