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Home Antibody All anti-TRPM4 antibodies

Anti-TRPM4 TRUEMAB Antibody clone 3C4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500370
  • anti-TRPM4 mouse monoclonal antibody,clone 3C4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413636) , 20ug
100ul 325 In Stock
CF500370
  • Carrier-free (BSA/glycerol-free) TRPM4 mouse monoclonal antibody,clone 3C4
100ug $450 3-4 weeks
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WB(1)
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Also for TRPM4 (NM_017636)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human TRPM4 expression vector
Clone Nameclone 3C4 IsotypeIgG1
Species ReactivityHuman Concentration1.20mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens transient receptor potential cation channel, subfamily M, member 4 (TRPM4), transcript variant 1
Alternative NamePFHB1B; TRPM4B
Database LinkNP_060106
FunctionCalcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRPM4 (RC216888, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRPM4.

 

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