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Anti-TRPM2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308572 Rabbit polyclonal antibody to TRPM2 (transient receptor potential cation channel, subfamily M, member 2) 100ul $325 3-7 Days
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 181 and 423 of TRPM2 (Uniprot ID#O94759)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: mouse, Rat) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 171kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: mouse (90%), Rat (90%)

Reference Data

Target NameHomo sapiens transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1
Alternative NameEREG1; KNP3; LTRPC2; NUDT9H; NUDT9L1; TRPC7
Database LinkNP_003298
Entrez Gene 7226 Human
Entrez Gene 28240 Mouse
Entrez Gene 294329 Rat
FunctionThe protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq]
Related PathwayIon Channels: Transient receptor potentialTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308572 diluted at 1:500.

IHC Image
Immunohistochemical analysis of paraffin-embedded MDAMB468 xenograft, using TRPM2(TA308572) antibody at 1:100 dilution.


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