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Home Antibody All anti-TRIM71 antibodies

Anti-TRIM71 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA320101 Rabbit Polyclonal TRIM71 Antibody 100ug $325 3-7 Days
LC422015 TRIM71 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenTRIM71 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TRIM71.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferTRIM71 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TRIM71 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tripartite motif containing 71, E3 ubiquitin protein ligase (TRIM71)
Alternative NameLIN-41; LIN41
Database LinkNP_001034200
Entrez Gene 131405 Human
Entrez Gene 636931 Mouse
Entrez Gene 301042 Rat
FunctionTRIM71 Antibody: TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TRIM71 in human brain tissue lysate with TRIM71 antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of TRIM71 in human brain tissue with TRIM71 antibody at 5 ug/mL.
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