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Home Antibody All anti-TRIM63 antibodies

Anti-TRIM63 Antibody

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SKU Description Amount Price Availability*  
TA308746
  • Rabbit Polyclonal antibody to MURF1 (tripartite motif-containing 63)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC410019) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 44 of MURF1 (Uniprot ID#Q969Q1)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Pig, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 40kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens tripartite motif containing 63, E3 ubiquitin protein ligase (TRIM63)
Alternative NameIRF; MURF1; MURF2; RNF28; SMRZ
Database LinkNP_115977
Entrez Gene 84676 Human
Entrez Gene 713802 Monkey
FunctionThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug whole cell lysate). A:Hep G2 . 10% SDS PAGE. TA308746 diluted at 1:1000
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Immunohistochemical analysis of paraffin-embedded Breast ca, using MURF1(TA308746) antibody at 1:500 dilution.
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Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MURF1 (TA308746) antibody at 1:200 dilution.
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