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Anti-TPSG1 TRUEMAB Antibody Clone OTI1E6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504027 TPSG1 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6) 100ul 325
In Stock
LC402219 TPSG1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504027 Carrier-free (BSA/glycerol-free) TPSG1 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6) 100ug $450 3-4 weeks
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Also for TPSG1 (NM_012467)
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 20-283 of human TPSG1(NP_036599) produced in E.coli.
Clone NameClone OTI1E6 IsotypeIgG1
Species ReactivityHuman Concentration0.8 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100,
Predicted MW Explanation 32 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tryptase gamma 1 (TPSG1)
Alternative NamePRSS31; TMT; trpA
Database LinkNP_036599
Entrez Gene 25823 Human
FunctionTryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related PathwayTransmembraneDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TPSG1 (RC222359, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TPSG1.

FC Image
HEK293T cells transfected with either RC222359 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TPSG1 antibody(TA504027), and then analyzed by flow cytometry.


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