Home Antibody All anti-TPP1 antibodies
Also for TPP1 (NM_000391)
|Recombinant fragment corresponding to a region within amino acids 66 and 324 of TPP1 (Uniprot ID#O14773)|
|Human (Predicted: Chimpanzee)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chimpanzee (100%)
|Homo sapiens tripeptidyl peptidase I (TPP1)|
|CLN2; GIG1; LPIC; SCAR7; TPP-1|
Entrez Gene 1200 Human
|This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate). A: A431 . B: H1299. C: Hela. 7.5% SDS PAGE. TA308203 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using TPP1(TA308203) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed A431, using TPP1(TA308203) antibody at 1:200 dilution.