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Home Antibody All anti-TPP1 antibodies

Anti-TPP1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308203 Rabbit Polyclonal antibody to TPP1 (tripeptidyl peptidase I) 100ul $325 In Stock
LC400137 TPP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 66 and 324 of TPP1 (Uniprot ID#O14773)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Chimpanzee) Concentration0.64mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 61kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens tripeptidyl peptidase I (TPP1)
Alternative NameCLN2; GIG1; LPIC; SCAR7; TPP-1
Database LinkNP_000382
Entrez Gene 1200 Human
FunctionThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]
Related PathwayProtease Lysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431 . B: H1299. C: Hela. 7.5% SDS PAGE. TA308203 diluted at 1:1000.

IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using TPP1(TA308203) antibody at 1:100 dilution.

IF Image
Immunofluorescence analysis of methanol-fixed A431, using TPP1(TA308203) antibody at 1:200 dilution.


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