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Home Antibody All anti-TPP1 antibodies

Anti-TPP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308203
  • Rabbit Polyclonal antibody to TPP1 (tripeptidyl peptidase I)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400137) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 66 and 294 of human TPP1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.64mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens tripeptidyl peptidase I (TPP1)
Alternative NameCLN2; GIG1; LPIC; SCAR7; TPP-1
Database LinkNP_000382
FunctionThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]
Related Pathway

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WB Image
A: A431 B: H1299 C: Hela (anti-TPP1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using TPP1(anti-TPP1 antibody) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using TPP1(anti-TPP1 antibody) antibody at 1:200 dilution.

 

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