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Home Antibody All anti-TP53I3 antibodies

Anti-TP53I3 Antibody


Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308561 Rabbit Polyclonal antibody to PIG3 (tumor protein p53 inducible protein 3) 100ul $325 In Stock
LC429226 TP53I3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for TP53I3 (NM_004881)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 332 of PIG3 (Uniprot ID#Q53FA7)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 36kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (88%)

Reference Data

Target NameHomo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 1
Alternative NamePIG3
Database LinkNP_004872
Entrez Gene 9540 Human
FunctionThe protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related PathwayDruggable Genome p53 signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. TA308561 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded H441 xenograft, using PIG3(TA308561) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A549, using PIG3 (TA308561) antibody at 1:200 dilution.


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