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Home Antibody All anti-TP53 antibodies

Anti-TP53 TRUEMAB Antibody clone 1D8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502851
  • TP53 mouse monoclonal antibody, clone 1D8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400186) , 20ug
100ul 325 In Stock
CF502851
  • Carrier-free (BSA/glycerol-free) TP53 mouse monoclonal antibody, clone 1D8
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(1)
IF(1)
FC(3)
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Also for TP53 (NM_000546)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TP53 (NP_000537) produced in HEK293T cell.
Clone Nameclone 1D8 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.71 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor protein p53 (TP53), transcript variant 1
Alternative NameBCC7; LFS1; P53; TRP53
Database LinkNP_000537
FunctionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq].
Related Pathway
Apoptosis
Cell cycle
Delta-Notch Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TP53 (RC200003, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TP53.</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TP53 monoclonal antibody.</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TP53 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA502851)</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
IF Image
Anti-TP53 mouse monoclonal antibody (TA502851) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TP53(RC200003).</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
FC Image
HEK293T cells transfected with either RC200003 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TP53 antibody(TA502851), and then analyzed by flow cytometry.</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
FC Image
Flow cytometric Analysis of Hela cells, using anti-TP53 antibody(TA502851),(Red), compared to a nonspecific negative control antibody,(Blue).</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-TP53 antibody(TA502851),(Red), compared to a nonspecific negative control antibody,(Blue).</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>

 

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