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Home Antibody All anti-TOLLIP antibodies

Anti-TOLLIP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306292
  • Rabbit Polyclonal TOLLIP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402724) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for TOLLIP (NM_019009)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTOLLIP antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human TOLLIP.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens toll interacting protein (TOLLIP)
Alternative NameIL-1RAcPIP
Database LinkNP_061882
FunctionToll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
Related Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of TOLLIP in rat brain cell lysate with TOLLIP antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of TOLLIP in THP-1 cells with TOLLIP antibody at 2 ug/mL.

 

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