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Home Antibody All anti-TNFRSF8 antibodies

Anti-TNFRSF8 TRUEMAB Antibody Clone OTI18D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA801647 TNFRSF8 mouse monoclonal antibody, clone OTI18D3 (formerly 18D3) 100ul $325 In Stock
LC420050 TNFRSF8 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF801647 Carrier-free (BSA/glycerol-free) TNFRSF8 mouse monoclonal antibody, clone OTI18D3 (formerly 18D3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(5)
FC(2)
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Also for TNFRSF8 (NM_001243)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 19-379 of human TNFRSF8 (NP_001234) produced in E.coli.
Clone NameClone OTI18D3 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, FC Suggested Dilutions WB 1:2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 61.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1
Alternative NameCD30; D1S166E; Ki-1
Database LinkNP_001234
Entrez Gene 943 Human
FunctionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF8 (RC219819, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF8.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647)
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Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647)
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Flow cytometric Analysis of K562 and Ramos cells, using anti-TNFRSF8 antibody(TA801647),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).(1:100)
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Flow cytometric Analysis of K562 cells, using anti-TNFRSF8 antibody(TA801647),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue). Dilution: 1:50
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