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Home Antibody All anti-THBD antibodies

Anti-THBD Antibody EPR4051

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307719
  • Rabbit monoclonal antibody against CD141(clone EPR4051)
100ul 325 In Stock
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WB(1)
IHC(6)
IF(1)
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Also for THBD (NM_000361)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human CD141 was used as an immunogen.
Clone NameEPR4051 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens thrombomodulin (THBD)
Alternative NameAHUS6; BDCA3; CD141; THPH12; THRM; TM
Database LinkNP_000352
Entrez Gene 7056 Human
FunctionThrombomodulin (THBD, CD141) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Defects in CD141 are a cause of thromboembolic disease, also known as inherited thrombophilia (1).
Related PathwayTransmembraneDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Thrombomodulin antibody [EPR4051]; All lanes : Anti-Thrombomodulin antibody [EPR4051] at 1/1000 dilution.Lane 1 : THP-1 cell lysate.Lane 2 : Human placenta lysate.Lane 3 : Human heart lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 60 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Thrombomodulin antibody [EPR4051]; TA307719, at 1/100 dilution, staining Thrombomodulin in Human placenta tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Thrombomodulin antibody [EPR4051]; TA307719, at 1/100 dilution, staining Thrombomodulin in Human squamous cervical carcinoma tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Thrombomodulin antibody [EPR4051](TA307719); Immunohistochemical analysis of paraffin embedded normal Human spleen tissue using TA307719 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Thrombomodulin antibody [EPR4051](TA307719); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA307719 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Thrombomodulin antibody [EPR4051](TA307719); Immunohistochemical analysis of paraffin embedded normal Human lung tissue using TA307719 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thrombomodulin antibody [EPR4051]; TA307719 staining Thrombomodulin in Human artery tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 20% serum for 60 minutes at 21°C; antigen retrieval was by heat mediation in a citrate buffer. Samples were incubated with primary antibody (1/200) for 16 hours at 4°C. A Biotin-conjugated Goatanti-rabbit polyclonal (1/200) was used as the secondary antibody.
IF Image
Immunocytochemistry/ Immunofluorescence - Thrombomodulin antibody [EPR4051]; TA307719, at 1/100 dilution, staining Thombomodulin in A431 cells by Immunofluorescence.

 

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