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Home Antibody All anti-TARDBP antibodies

Anti-TARDBP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309253
  • Rabbit Anti-TDP43 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402137) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for TARDBP (NM_007375)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to amino acid residues C-terminal to the caspase-cleavage site (between D219 and V220) of human TDP-43.
Clone Name IsotypeIgG
Species Reactivityhuman, rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000, IHC: 1:250
Buffer100 ul in PBS + 30% glycerol
Purification Affinity Purified

Reference Data

Target NameHomo sapiens TAR DNA binding protein (TARDBP)
Alternative NameALS10; TDP-43
Database LinkNP_031401
FunctionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq].
Related Pathway

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WB Image
Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 43 kDa TDP43 protein.

 

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