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Home Antibody All anti-NAE1 antibodies

Anti-NAE1 TRUEMAB Antibody Clone 1E10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA804384
  • Purified NAE1 mouse monoclonal antibody,clone 1E10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422668) , 20ug
100ul 325 In Stock
CF804384
  • Carrier-free (BSA/glycerol-free) NAE1 mouse monoclonal antibody,clone 1E10
100ug $450 3 Days
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WB(1)
IHC(3)
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Also for NAE1 (NM_001018160)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-274 of human NAE1 (NP_001018170) produced in E.coli.
Clone NameClone 1E10 IsotypeIgG1
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 3
Alternative NameA-116A10.1; APPBP1; HPP1; ula-1
Database LinkNP_001018170
FunctionThe protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA804384)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA804384)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA804384)

 

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