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Anti-NAE1 TRUEMAB Antibody Clone OTI1E10
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for NAE1 (NM_001018160)
|Human recombinant protein fragment corresponding to amino acids 1-274 of human NAE1 (NP_001018170) produced in E.coli.|
|| WB 1:2000, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 3|
|A-116A10.1; APPBP1; HPP1; ula-1|
Entrez Gene 8883 Human
|The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| Alzheimer's disease|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804384)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804384)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804384)