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Home Antibody All anti-IFIH1 antibodies

Anti-IFIH1 TRUEMAB Antibody Clone OTI11C11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA803670 IFIH1 (MDA5) mouse monoclonal antibody, clone OTI11C11 (formerly 11C11) 100ul $325 In Stock
LC411723 IFIH1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803670 Carrier-free (BSA/glycerol-free) IFIH1 mouse monoclonal antibody, clone OTI11C11 (formerly 11C11) 100ug $450 3 Days
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WB(1)
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Also for IFIH1 (NM_022168)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IFIH1 (NP_071451) produced in HEK293T cell.
Clone NameClone OTI11C11 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interferon induced with helicase C domain 1 (IFIH1)
Alternative NameAGS7; Hlcd; IDDM19; MDA-5; MDA5; RLR-2
Database LinkNP_071451
Entrez Gene 64135 Human
FunctionDEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012].
Related Pathway RIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IFIH1 (RC215661, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IFIH1.
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