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Home Antibody All anti-CD8A antibodies

Anti-CD8A TRUEMAB Antibody Clone OTI3H6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802079 CD8A mouse monoclonal antibody,clone OTI3H6 100ul $325 In Stock
LC419749 CD8A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802079 Carrier-free (BSA/glycerol-free) CD8A mouse monoclonal antibody,clone OTI3H6 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(2)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-182 of human CD8A (NP_001759) produced in E.coli.
Clone NameClone OTI3H6 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 23.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD8a molecule (CD8A), transcript variant 1
Alternative NameCD8; Leu2; MAL; p32
Database LinkNP_001759
Entrez Gene 925 Human
FunctionThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Related PathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD8A (RC206608, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD8A.
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CD8A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802079)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-CD8A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802079)
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