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Home Antibody All anti-PAX5 antibodies

Anti-PAX5 TRUEMAB Antibody Clone4F9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA801969
  • PAX5 mouse monoclonal antibody,clone 4F9
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413830) , 20ug
100ul 325 In Stock
CF801969
  • Carrier-free (BSA/glycerol-free) PAX5 mouse monoclonal antibody,clone 4F9
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(2)
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Also for PAX5 (NM_016734)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PAX5 (NP_057953) produced in E.coli.
Clone NameClone4F9 IsotypeIgG2a
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens paired box 5 (PAX5), transcript variant 1
Alternative NameALL3; BSAP
Database LinkNP_057953
FunctionThis gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAX5 (RC222785, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PAX5.
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PAX5 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801969)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PAX5 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801969)

 

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