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Home Antibody All anti-PIK3C2A antibodies

Anti-PIK3C2A TRUEMAB Antibody Clone OTI4H9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA801695 PIK3C2A mouse monoclonal antibody, clone OTI4H9 (formerly 4H9) 100ul $325 In Stock
LC400940 PIK3C2A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF801695 Carrier-free (BSA/glycerol-free) PIK3C2A mouse monoclonal antibody, clone OTI4H9 (formerly 4H9) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
IHC(4)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 230-560 of human PIK3C2A (NP_002636) produced in E.coli.
Clone NameClone OTI4H9 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 190.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (PIK3C2A)
Alternative NameCPK; PI3-K-C2(ALPHA); PI3-K-C2A
Database LinkNP_002636
Entrez Gene 5286 Human
FunctionThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Inositol phosphate metabolismMetabolic pathwaysPhosphatidylinositol signaling system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 230-560 of human PIK3C2A (NP_002636) were separated by SDS-PAGE and immunoblotted with anti-PIK3C2A.
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Western blot analysis of  HT29 cell lysate (35ug) by using anti-PIK3C2A monoclonal antibody. Dilution: 1:500
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PIK3C2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801695)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PIK3C2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801695)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PIK3C2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801695)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PIK3C2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801695)
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