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Home Antibody All anti-MMADHC antibodies

Anti-MMADHC TRUEMAB Antibody Clone OTI1G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800573 MMADHC mouse monoclonal antibody, clone OTI1G4 (formerly 1G4) 100ul $325 In Stock
LC414395 MMADHC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800573 Carrier-free (BSA/glycerol-free) MMADHC mouse monoclonal antibody, clone OTI1G4 (formerly 1G4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
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Also for MMADHC (NM_015702)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 39-296 of human MMADHC (NP_056517) produced in E.coli.
Clone NameClone OTI1G4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 32.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria (MMADHC)
Alternative NameC2orf25; cblD; CL25022
Database LinkNP_056517
Entrez Gene 27249 Human
FunctionThis gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMADHC (RC204801, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMADHC.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MMADHC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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