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Anti-CUL4B TRUEMAB Antibody Clone 7F8
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CUL4B (NM_003588)
|Human recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.|
|Human , Dog , Rat , Monkey , Mouse
|| WB 1:2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cullin 4B (CUL4B), transcript variant 1|
|CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2|
Entrez Gene 8450 Human
Entrez Gene 72584 Mouse
Entrez Gene 302502 Rat
Entrez Gene 696410 Monkey
Entrez Gene 492102 Dog
|This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| Nucleotide excision repairUbiquitin mediated proteolysis|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CUL4B (RC206935, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CUL4B.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CUL4B monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).