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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-CUL4B antibodies

Anti-CUL4B TrueMAB Antibody Clone 7G10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA800391
  • Purified CUL4B mouse monoclonal antibody,clone 7G10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418558) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF800391
  • Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody,clone 7G10
100ug $450 8-10 Days Add to Shopping Cart
WB(1)
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Also for CUL4B (NM_003588)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens cullin 4B (CUL4B), transcript variant 1
Synonyms:MRXHF2; MRXS15; MRXSC; SFM2
ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 7G10 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BackgroundThis gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CUL4B (RC206935, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CUL4B.

 

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