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Home Antibody All anti-BIRC3 antibodies

Anti-BIRC3 TRUEMAB Antibody Clone OTI3G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800063 BIRC3 (cIAP2) mouse monoclonal antibody, clone OTI3G4 (formerly 3G4) 100ul $379 In Stock
LC420093 BIRC3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800063 Carrier-free (BSA/glycerol-free) BIRC3 mouse monoclonal antibody, clone OTI3G4 (formerly 3G4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
FC(1)
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Also for BIRC3 (NM_001165)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 255-529 of human BIRC3 (NP_001156) produced in E.coli.
Clone NameClone OTI3G4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, FC Suggested Dilutions WB 1:500~2000, FLOW 1:100,
Predicted MW Explanation 68.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 3 (BIRC3), transcript variant 1
Alternative NameAIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
Database LinkNP_001156
Entrez Gene 330 Human
FunctionThis gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011].
Related PathwayDruggable Genome Ubiquitin mediated proteolysisApoptosisFocal adhesionNOD-like receptor signaling pathwayPathways in cancerSmall cell lung cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC3 (RC207764, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC3.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-BIRC3 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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HEK293T cells transfected with either RC207764 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-BIRC3 antibody(TA800063), and then analyzed by flow cytometry.
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