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Anti-MECOM GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for MECOM (NM_001105077)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
||WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens MDS1 and EVI1 complex locus (MECOM), transcript variant 1|
|AML1-EVI-1; EVI1; MDS1; MDS1-EVI1; PRDM3|
Entrez Gene 2122 Human
|EVI1 (ecotropic viral integration site 1) was originally identified as a gene located in the integration site of ecotropic retroviruses in the mouse genome that resulted in myeloid tumors. EVI1 is a zinc finger transcription factor that plays an important role in development and leukemogenesis. It is an oncogene that can have effects on cell proliferation, differentiation, and apoptosis. Chromosomal translocations involving EVI1 result in chronic myelogenous leukemia (CML). Alternate names for EVI1 include AML1-EVI-1 fusion protein, PRDM3, and MDS1-EV1.|
|Transcription FactorsDruggable Genome MAPK signaling pathwayPathways in cancerChronic myeloid leukemia|
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