Home Antibody All anti-PTPRN antibodies
Anti-PTPRN GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for PTPRN (NM_002846)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|Human , Monkey , Mouse
|| WB 1:5000~20000,ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1|
|IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N|
Entrez Gene 5798 Human
Entrez Gene 19275 Mouse
Entrez Gene 702826 Monkey
|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.|
|TransmembraneDruggable Genome Type I diabetes mellitus|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPRN (RC220230, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPRN.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PTPRN polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).