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Home Antibody All anti-SIPA1 antibodies
UltraMAB

Anti-SIPA1 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590387 Rabbit Polyclonal SIPA1 Antibody 100ug $325 In Stock
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IHC(1)
IF(1)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.02555 mg/ml
Guaranteed Application *ELISA, IHC, IF Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:600; IF: 1:150
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens signal-induced proliferation-associated 1 (SIPA1), transcript variant 1
Alternative NameSPA1
Database LinkNP_694985
Entrez Gene 6494 Human
FunctionThe product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq]
Related PathwayES Cell Differentiation/IPSDruggable Genome Leukocyte transendothelial migration

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ELISA: SIPA1 Antibody - Affinity Purified
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Immunohistochemical staining of human rectum shows strong nuclear and cytoplasmic positivity in glandular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
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Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleoli & nucleus but not nucleoli.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
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