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Anti-RELN GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for RELN (NM_173054)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens reelin (RELN), transcript variant 2|
|LIS2; PRO1598; RL|
Entrez Gene 5649 Human
|Reelin is an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Reelin regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and ApoER2 induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).|
|Druggable Genome Focal adhesionECM-receptor interaction|
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