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Home Antibody All anti-XRCC1 antibodies
UltraMAB

Anti-XRCC1 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590221
  • Rabbit Polyclonal XRCC1 Antibody
100ug 325 In Stock
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(10)
ELISA(1)
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Also for XRCC1 (NM_006297)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Monkey Concentration0.87mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)
Alternative NameRCC
Database LinkNP_006288
Entrez Gene 7515 Human
Entrez Gene 711457 Monkey
FunctionXRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA Ligase III-a.
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (RC204952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-XRCC1 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
ELISA Image
ELISA: XRCC1 Antibody
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-XRCC1 rabbit polyclonal antibody. (TA590221)

 

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