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Home Antibody All anti-MCM6 antibodies
UltraMAB

Anti-MCM6 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590213
  • Rabbit Polyclonal MCM6 Antibody
100ug $325 In Stock
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WB(2)
IHC(4)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Dog , Monkey , Mouse Concentration1.07664
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:5000~20000, IHC 1:150, ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens minichromosome maintenance complex component 6 (MCM6)
Alternative NameMCG40308; Mis5; P105MCM
Database LinkNP_005906
Entrez Gene 4175 Human
Entrez Gene 17219 Mouse
Entrez Gene 707651 Monkey
Entrez Gene 476131 Dog
FunctionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Related PathwayStem cell - PluripotencyTranscription Factors DNA replicationCell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCM6 (RC207097, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MCM6.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MCM6 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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ELISA: MCM6 Antibody
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Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-MCM6 rabbit polyclonal antibody. (TA590213)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-MCM6 rabbit polyclonal antibody. (TA590213)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MCM6 rabbit polyclonal antibody. (TA590213)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-MCM6 rabbit polyclonal antibody. (TA590213)
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