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Home Antibody All anti-TNFRSF10B antibodies
UltraMAB

Anti-TNFRSF10B GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590163 Rabbit Polyclonal TRAIL-R2 Antibody 100ug $325 In Stock
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ELISA(1)
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Also for TNFRSF10B (NM_003842)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.99mg/ml
Guaranteed Application *ELISA Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000; FC 1:10-1:1000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1
Alternative NameCD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Database LinkNP_003833
Entrez Gene 8795 Human
FunctionThe protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionp53 signaling pathwayApoptosisNatural killer cell mediated cytotoxicity

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: DR5 Antibody
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