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Home Antibody All anti-MYC antibodies

Anti-MYC TRUEMAB Antibody Clone OTI5E9G2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA507203 MYC mouse monoclonal antibody, clone OTI5E9G2 (formerly 5E9G2) 100ul $325 In Stock
LC400876 MYC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF507203 Carrier-free (BSA/glycerol-free) MYC mouse monoclonal antibody, clone OTI5E9G2 (formerly 5E9G2) 100ug $450 3-4 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IF(2)

OriGene Data

ImmunogenFull length human recombinant protein of human Myc (NP_002458) produced in 293T
Clone NameClone OTI5E9G2 IsotypeIgG2a
Species ReactivityHuman , Dog , Rat , Monkey Concentration0.33 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:200~4000, IF 1:100,
Predicted MW Explanation 50.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)
Alternative NamebHLHe39; c-Myc; MRTL; MYCC
Database LinkNP_002458
Entrez Gene 4609 Human
Entrez Gene 24577 Rat
Entrez Gene 694626 Monkey
Entrez Gene 403924 Dog
FunctionThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayStem cell relevant signaling - Wnt Signaling pathwayStem cell - PluripotencyEmbryonic stem cellsInduced pluripotent stem cellsTranscription FactorsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCell cycleWnt signaling pathwayTGF-beta signaling pathwayJak-STAT signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYC (RC201611, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYC.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MYC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Anti-MYC mouse monoclonal antibody (TA507203) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYC(RC201611).
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Immunofluorescent staining of HeLa cells using anti-MYC mouse monoclonal antibody (TA507203).
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