Home Antibody All anti-IL1R2 antibodies
Anti-IL1R2 TRUEMAB Antibody Clone 3C6
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for IL1R2 (NM_004633)
|Full length human recombinant protein of human IL1R2(NP_004624) produced in HEK293T cell.|
|| WB 1:1000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens interleukin 1 receptor, type II (IL1R2), transcript variant 1|
|CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB|
Entrez Gene 7850 Human
|The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]. |
|TransmembraneDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionHematopoietic cell lineage|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1R2 (RC221860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1R2.