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Home Antibody All anti-MMP13 antibodies

Anti-MMP13 TRUEMAB Antibody Clone 3F5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506721
  • MMP13 mouse monoclonal antibody,clone 3F5
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400869) , 20ug
100ul $325 In Stock
CF506721
  • Carrier-free (BSA/glycerol-free) MMP13 mouse monoclonal antibody,clone 3F5
100ug $450 8-10 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 104-471 of human MMP13 (NP_002418) produced in HEK293T cell.
Clone NameClone 3F5 IsotypeIgG2a
Species ReactivityHuman Concentration1.00mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:4000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens matrix metallopeptidase 13 (collagenase 3) (MMP13)
Alternative NameCLG3; MANDP1
Database LinkNP_002418
FunctionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP13 (RC224156, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP13.
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506721)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506721)

 

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