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Home Antibody All anti-IDO1 antibodies

Anti-IDO1 TRUEMAB Antibody Clone OTI2G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA506367 IDO1 mouse monoclonal antibody, clone OTI2G4 (formerly 2G4) 100ul
30ul
$379 In Stock
LC400784 IDO1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506367 Carrier-free (BSA/glycerol-free) IDO1 mouse monoclonal antibody, clone OTI2G4 (formerly 2G4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(1)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human IDO1(NP_002155) produced in HEk293T cell.
Clone NameClone OTI2G4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:200~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 45.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens indoleamine 2,3-dioxygenase 1 (IDO1)
Alternative NameIDO; IDO-1; INDO
Database LinkNP_002155
Entrez Gene 3620 Human
FunctionThis gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].
Related PathwayDruggable Genome Tryptophan metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDO1 (RC206592, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IDO1.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-IDO1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-IDO1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506367)
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Anti-IDO1 mouse monoclonal antibody (TA506367) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDO1(RC206592).
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