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Anti-RTKN TrueMAB Antibody Clone 1A4
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for RTKN (NM_033046)
|Full length human recombinant protein of human RTKN(NP_149035) produced in HEK293T cell.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
|| WB 1:2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens rhotekin (RTKN), transcript variant 2|
|This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RTKN (RC204517, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RTKN.
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
Anti-RTKN mouse monoclonal antibody (TA505051) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RTKN(RC204517).