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 Home All anti-RTKN antibodies

Anti-RTKN TrueMAB Antibody Clone 1A4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA505051
  • RTKN mouse monoclonal antibody,clone 1A4
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403228) , 20ug
 100ul $325 In Stock
CF505051
  • Carrier-free (BSA/glycerol-free) RTKN mouse monoclonal antibody,clone 1A4
100ug $450 3 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(4)
IF(1)
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Also for RTKN (NM_033046)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RTKN(NP_149035) produced in HEK293T cell.
Clone NameClone 1A4 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens rhotekin (RTKN), transcript variant 2
Alternative NameB5
Database LinkNP_149035
FunctionThis gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RTKN (RC204517, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RTKN.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-RTKN mouse monoclonal antibody. (TA505051)
IF Image
Anti-RTKN mouse monoclonal antibody (TA505051) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RTKN(RC204517).

 

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