Anti-DOK7 Antibody, Clone 1F7

Also for DOK7 (NM_173660)

Gene Name	Homo sapiens docking protein 7 (DOK7), transcript variant 1
Synonyms:	C4orf25; CMS1B
Immunogen	Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Name	Clone 1F7	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Background	The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOK7 (RC219267, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOK7.

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IHC Image

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-DOK7 mouse monoclonal antibody. (TA504789)

IF Image

Anti-DOK7 mouse monoclonal antibody (TA504789) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DOK7(RC219267).

FC Image

HEK293T cells transfected with either RC219267 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DOK7 antibody(TA504789), and then analyzed by flow cytometry.

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Anti-DOK7 TrueMAB Antibody Clone 1F7

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